WSU's campuses cover an area of approximately 1000 kilometers in the Eastern Cape, making it accessible to students in a vast expancse of the underdeveloped eastern half of the Province, home to over 4,5 million people.

With delivery sites in Buffalo City, Butterworth, Mthatha and Queenstown, WSU will commence with six (6) faculties; over 20,000 students; close to 1,000 staff and an operating budget of almost half a billion rand.

WSU's main campus is situated in Nelson Mandela Drive, Mthata (formerly the main campus of Unitra). ECT's Zamkulungisa Heights campus nearby provides additional infrastructure for WSU.

In Butterworth the former main campus of ECT in Ibika and the former Unitra satellite campus in the Vuli Valley provide further accessibility for students in the under-developed areas of the former Transkei.

Further inland, the form Queenstown satellite campus of ECT is the sole provider of higher education in this area.

In Buffalo City, WSU has several sites of delivery close to commerce and industry in East London, where were formerly campuses of both BT and ECT. These are at Potsdam (formerly the main campus of BT), Chiselhurst, College Street, Cambridge Street and Absa Stadium.

WSU also has a delivery site in Bhisho, the capital of the Eastern Cape Province.